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Are We Ready? Resilience as a Biomarker for a “Healthy” Gut Microbiome
Gut microbiome “resilience" is a commonly applied metric in gut microbiome research, a characteristic that may be positive or negative depending upon the research question and context. Does “resilience” have potential as a biomarker for healthier gut microbiomes? This session will review varying perspectives on how resilience, stability, and other related properties are defined and measured. Population variability in resilience, including responders vs. non-responders compared to the “average” response will be discussed. Speakers will review how resilience is conferred against diverse stressors such as diet, food-borne pathogens, antibiotics, or other factors. Other key topics will include how diet affects resilience in humans (both positive and negative – and including food safety considerations), and related mechanisms; and recovery, or how the gut microbiome can be influenced to return to “baseline” following perturbation. This session is a collaboration between IAFNS and ASN’s Nutritional Microbiology GEM.
Originally presented at NUTRITION 2023, ASN's flagship meeting which was held July 22-25, 2023 in Boston, MA.
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Speakers
Curtis Huttenhower, PhD
Professor, Biostatistics Department, Harvard T.H. Chan School of Public Health
Abigail Johnson, PhD, RD
Assistant Professor, School of Public Health, University of Minnesota
J. Philip Karl, PhD, RD
Nutrition Physiologist, Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine
Jotham Suez, PhD
Assistant Professor, Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health
Learning Objectives
- Define gut microbiome resilience, a common metric used in gut microbiome research
- Explain population variability in resilience
- Review how resilience is conferred against diverse stressors such as diet, food-borne pathogens, antibiotics, etc.
This activity includes the following presentations:
Introduction
J. Philip Karl, PhD, RD
Nutrition Physiologist, Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine
Gut Microbiome Resilience: Measurement, Mechanisms & Meaning
Curtis Huttenhower, PhD
Professor, Biostatistics Department, Harvard T.H. Chan School of Public Health
Does Diet Affect Resilience?
Abigail Johnson, PhD, RD
Assistant Professor, School of Public Health, University of Minnesota
Using Dietary Interventions to Recover from a Microbiome-Disrupting Event
Jotham Suez, PhD
Assistant Professor, Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health
Panel Discussion
Curtis Huttenhower, PhD
Professor, Biostatistics Department, Harvard T.H. Chan School of Public Health
Abigail Johnson, PhD, RD
Assistant Professor, School of Public Health, University of Minnesota
J. Philip Karl, PhD, RD
Nutrition Physiologist, Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine
Jotham Suez, PhD
Assistant Professor, Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health
Disclosure Policy
It is the policy of the American Society of Nutrition, in compliance with the Standards for Integrity and Independence in Accredited Continuing Education to ensure that education presents learners with only accurate, balanced, and scientifically justified recommendations and protects learners from promotion, marketing, and commercial bias. ASN requires disclosure of all financial interest that the planning committee (including ASN staff) or faculty members have with ineligible companies. All faculty and contributors to this continuing education activity have disclosed any relevant financial relationship that may have direct bearing on the subject matter of this program. Specific disclosure information is in the course materials.
The American Society for Nutrition supports fair and unbiased participation of individuals in its education activities. Any real or potential conflicts of interest must be identified and managed. All relevant financial relationships with commercial interests that directly impact and/or might conflict with ASN activities must be disclosed, or disclosure that no relevant financial relationships exist must be documented. Other relationships that could cause private interests to conflict with professional interests must also be disclosed. This policy is intended to openly identify any potential conflict so that participants in an education activity are able to form their own judgments about the presentation. In addition, disclosure must be made of presentations on drugs or devices or uses of drugs or devices that have not been approved by the Food and Drug Administration.
Speakers
Curtis Huttenhower, PhD, Professor, Biostatistics Department, Harvard T.H. Chan School of Public Health
Disclosures: Seres Therapeutics: Advisory Committee/Board Member (Ongoing); Consultant (Ongoing); Stock Shareholder (excluding mutual funds) (Ongoing); ZOE: Advisory Committee/Board Member (Ongoing)
All of the relevant financial relationships listed for this individual have been mitigated.
Abigail Johnson, PhD, RD, Assistant Professor, School of Public Health, University of Minnesota
No relevant financial relationship(s) with ineligible companies to disclose.
J. Philip Karl, PhD, RD, Nutrition Physiologist, Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine
No relevant financial relationship(s) with ineligible companies to disclose.
Jotham Suez, PhD, Assistant Professor, Department of Molecular Microbiology & Immunology, Johns Hopkins Bloomberg School of Public Health
No relevant financial relationship(s) with ineligible companies to disclose.
Planners
The following individuals served on the NUTRITION 2023 Scientific Program Committee. The session titled 'Are We Ready? Resilience as a Biomarker for a “Healthy” Gut Microbiome' was included in the scientific program of NUTRITION 2023, ASN's flagship meeting which was held from July 22-25, 2023.
Paola Baratto, MS, Rutgers University
No relevant financial relationship(s) with ineligible companies to disclose.
Nicolaas Deutz, MD, PhD, Texas A&M University
Disclsoures: Abbott: Speaker Fees
All of the relevant financial relationships listed for this individual have been mitigated.
Bradley Ferguson, PhD, University of Nevada, Reno
No relevant financial relationship(s) with ineligible companies to disclose.
Martha Field, PhD, Cornell University
No relevant financial relationship(s) with ineligible companies to disclose.
Daniel Hoffman, PhD, Rutgers University
No relevant financial relationship(s) with ineligible companies to disclose.
Hannah Holscher, PhD, RD, University of Illinois at Urbana-Champaign
Disclosures: Almond Board of California; Grant/Research Support; Beneo: Speaker/Speaker's Bureau; Bio-Cat: Grant/Research Support; General Mills Inc.: Grant/Research Support; Hass Avocado Board: Grant/Research Support; ISAPP: Speaker/Speaker's Bureau; National Dairy Council: Speaker/Speaker's Bureau; National Honey Board:Grant/Research Support; Tate & Lyle: Grant/Research Support
All of the relevant financial relationships listed for this individual have been mitigated.
Frank Hu, MD, MPH, PhD, Harvard T.H. Chan School of Public Health
No relevant financial relationship(s) with ineligible companies to disclose.
Zhaoping Li, MD, PhD, UCLA
Nutrient Institute (Scientific Advisory Board Member)
All of the relevant financial relationships listed for this individual have been mitigated.
Laura Murray-Kolb, PhD, Purdue University
No relevant financial relationship(s) with ineligible companies to disclose.
Kathryn Porter Starr, PhD, RD, Duke University School of Medicine and Durham VA Medical Center
No relevant financial relationship(s) with ineligible companies to disclose.
Lewis Rubin, MD, Georgetown University Medical Center
Disclosures: Abbott Nutrition: Grant/Research Support
All of the relevant financial relationships listed for this individual have been mitigated.
Anna Thalacker-Mercer, PhD, The University of Alabama at Birmingham
No relevant financial relationship(s) with ineligible companies to disclose.
Staff
Michelle Crispino, CAE, DES, American Society for Nutrition
No relevant financial relationship(s) with ineligible companies to disclose.
Gwen Twillman, American Society for Nutrition
No relevant financial relationship(s) with ineligible companies to disclose.
Continuing education credit is not available for this activity. A Certificate of Attendance can be downloaded by learners who complete the course.
Available Credit
- 1.50 Attendance
Learners are eligible to download a Certificate of Attendance upon activity completion. A Certificate of Attendance confirms the learner has completed the activity and does not confer any continuing education credit to the learner from ASN.
Price
Special ASN Member Benefit - 50% Off for Members!
ASN members receive this course for 50% off. Login now to get the $10 special member rate. If you do not see the member rate displayed for you after logging in, please contact discover@nutrition.org.
Not an ASN member? Click here to join ASN to receive member rates on all DiscoverNUTRITION products!