Sponsored By: Kyowa Hakko USA

This Sponsored Satellite Program was originally presented at NUTRITION 2024, ASN's flagship meeting which was held June 29 to July 2, 2024 in Chicago, IL.

Explore the groundbreaking research unveiling the molecular and functional impacts of citicoline on brain health. This program delves into the mechanisms underlying the neuroprotective effects of citicoline, utilizing an integrative high-resolution transcriptomic approach in both in vivo and human cell systems. Through in-depth analysis of citicoline's effects on a human iPSC-derived tri-culture system, comprising cortical neurons, astrocytes, and microglia cells, discover how this endogenously generated nucleotide enhances cognitive function and behavior. Gain insights into the potential of Cognizin® citicoline supplementation in combating cognitive decline and promoting brain aging.

Learning Objectives

• Describe transcriptome-based indication discovery which allows the identification of biological features that indicate the state of individual health
• Evaluate the potential therapeutic implications of citicoline supplementation for cognitive function and aging based on groundbreaking research findings on the molecular mechanisms underlying the neuroprotective effects of citicoline
• Discuss the importance of further investigation to elucidate the comprehensive molecular underpinnings of citicoline's mechanism of action in maintaining brain health